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1

Alcohol Metabolism

Cederbaum, Arthur I.

Journal:

Clinics in Liver Disease

Year:

2012

Language:

english

File:

PDF, 330 KB

english, 2012

2

Role of oxidative stress in alcohol-induced liver injury

Arthur I. Cederbaum, Yongke Lu, Defeng Wu

Journal:

Archives of Toxicology

Year:

2009

Language:

english

File:

PDF, 934 KB

english, 2009

3

Inhibition of CYP2E1 catalytic activity in vitro by S-adenosyl-l-methionine

Andres A. Caro, Arthur I. Cederbaum

Journal:

Biochemical Pharmacology

Year:

2005

Language:

english

File:

PDF, 455 KB

english, 2005

4

Introduction—serial review: alcohol, oxidative stress and cell injury

Arthur I. Cederbaum

Journal:

Free Radical Biology and Medicine

Year:

2001

Language:

english

File:

PDF, 27 KB

english, 2001

5

O XIDATIVE S TRESS , T OXICOLOGY , AND P HARMACOLOGY OF CYP2E1*

Caro, Andres A., Cederbaum, Arthur I.

Journal:

Annual Review of Pharmacology

Year:

2004

Language:

english

File:

PDF, 227 KB

english, 2004

6

Increased oxidation of ethylene glycol to formaldehyde by microsomes after ethanol treatment: role of oxygen radicals and cytochrome P450

Ewa Kukielka, Arthur I. Cederbaum

Journal:

Toxicology Letters

Year:

1995

Language:

english

File:

PDF, 705 KB

english, 1995

7

Oxidative Stress and Alcoholic Liver Disease

Wu, Defeng, Cederbaum, Arthur

Journal:

Seminars in Liver Disease

Year:

2009

Language:

english

File:

PDF, 165 KB

english, 2009

8

Transcriptome-based repurposing of apigenin as a potential anti-fibrotic agent targeting hepatic stellate cells

Hicks, Daniel F., Goossens, Nicolas, Blas-García, Ana, Tsuchida, Takuma, Wooden, Benjamin, Wallace, Michael C., Nieto, Natalia, Lade, Abigale, Redhead, Benjamin, Cederbaum, Arthur I, Dudley, Joel T.,

Journal:

Scientific Reports

Year:

2017

Language:

english

File:

PDF, 1.07 MB

english, 2017

9

Rapid decrease of cytochrome P-450IIE1 in primary hepatocyte culture and its maintenance by added 4-methylpyrazole

De Feng Wu, Liviu Clejan, Barry Potter, Dr. Arthur I. Cederbaum

Journal:

Year:

1990

Language:

english

File:

PDF, 1.26 MB

english, 1990

10

Presence of functionally active cytochrome P-450IIE1 in the plasma membrane of rat hepatocytes

Defeng Wu, Dr. Arthur I. Cederbaum

Journal:

Year:

1992

Language:

english

File:

PDF, 1.16 MB

english, 1992

11

Induction of cytochrome P450 2E1 increases hepatotoxicity caused by Fas agonistic Jo2 antibody in mice

Xiaodong Wang, Yongke Lu, Arthur I. Cederbaum

Journal:

Year:

2005

Language:

english

File:

PDF, 511 KB

english, 2005

12

Alcohol and oxidative liver injury

Aparajita Dey, Arthur I. Cederbaum

Journal:

Year:

2006

Language:

english

File:

PDF, 562 KB

english, 2006

13

Nrf2 is increased by CYP2E1 in rodent liver and HepG2 cells and protects against oxidative stress caused by CYP2E1

Pengfei Gong, Arthur I. Cederbaum

Journal:

Year:

2006

Language:

english

File:

PDF, 259 KB

english, 2006

14

Enhancement by pyrazole of lipopolysaccharide-induced liver injury in mice: Role of cytochrome P450 2E1 and 2A5

Yongke Lu, Arthur I. Cederbaum

Journal:

Year:

2006

Language:

english

File:

PDF, 2.26 MB

english, 2006

15

Induction of cytochrome promotes liver injury in ob/ob mice

Aparajita Dey, Arthur I. Cederbaum

Journal:

Year:

2007

Language:

english

File:

PDF, 1.53 MB

english, 2007

16

Cytochrome P4502E1 sensitizes to tumor necrosis factor alpha–induced liver injury through activation of mitogen-activated protein kinases in mice

Defeng Wu, Arthur Cederbaum

Journal:

Year:

2008

Language:

english

File:

PDF, 1.92 MB

english, 2008

17

Cytochrome P450 2E1 contributes to ethanol-induced fatty liver in mice

Yongke Lu, Jian Zhuge, Xiaodong Wang, Jingxiang Bai, Arthur I. Cederbaum

Journal:

Year:

2008

Language:

english

File:

PDF, 2.62 MB

english, 2008

18

Hepatotoxicity mediated by pyrazole (cytochrome P450 2E1) plus tumor necrosis factor alpha treatment occurs in c-Jun N-terminal kinase 2−/− but not in c-Jun N-terminal kinase 1−/− mice

Xiaodong Wang, Defeng Wu, Lili Yang, Arthur I. Cederbaum

Journal:

Year:

2011

Language:

english

File:

PDF, 6.42 MB

english, 2011

19

Ethanol upregulates pro-fibrogenic connective tissue growth factor (CTGF) gene expression in HepG2 cells via cytochrome P450 2E1-mediated ethanol oxidation

Masahiro Konishi, Shinzo Kato, Mikio Kajihara, Arthur Cederbaum, Hiromasa Ishii

Journal:

Hepatology Research

Year:

2004

Language:

english

File:

PDF, 310 KB

english, 2004

20

Pyrazole induced oxidative liver injury independent of CYP2E1/2A5 induction due to Nrf2 deficiency

Yongke Lu, Pengfei Gong, Arthur I. Cederbaum

Journal:

Year:

2008

Language:

english

File:

PDF, 1.36 MB

english, 2008

21

CYP2E1 overexpression inhibits microsomal Ca2+-ATPase activity in HepG2 cells

Andres A. Caro, Kerry L. Evans, Arthur I. Cederbaum

Journal:

Year:

2009

Language:

english

File:

PDF, 547 KB

english, 2009

22

Ethanol inhibits the JAK-STAT signaling pathway in freshly isolated rat hepatocytes but not in cultured hepatocytes or HepG2 cells: evidence for a lack of involvement of ethanol metabolism

Jianping Chen, Dahn L Clemens, Arthur I Cederbaum, Bin Gao

Journal:

Clinical Biochemistry

Year:

2001

Language:

english

File:

PDF, 372 KB

english, 2001

23

Iron and CYP2E1-dependent oxidative stress and toxicity

Arthur I. Cederbaum

Journal:

Year:

2003

Language:

english

File:

PDF, 111 KB

english, 2003

24

CYP2E1-dependent toxicity and up-regulation of antioxidant genes

Montserrat Marí, Defeng Wu, Natalia Nieto, Arthur I. Cederbaum

Journal:

Journal of Biomedical Science

Year:

2001

Language:

english

File:

PDF, 982 KB

english, 2001

25

CYP2E1 potentiation of LPS and TNFα-induced hepatotoxicity by mechanisms involving enhanced oxidative and nitrosative stress, activation of MAP kinases, and mitochondrial dysfunction

Yongke Lu, Arthur I. Cederbaum

Journal:

Genes & Nutrition

Year:

2010

Language:

english

File:

PDF, 1.55 MB

english, 2010

26

Cytochrome P450 2E1-dependent oxidant stress and upregulation of anti-oxidant defense in liver cells

Arthur I Cederbaum

Journal:

Journal of Gastroenterology and Hepatology

Year:

2006

Language:

english

File:

PDF, 101 KB

english, 2006

27

Glycerol Increases Content and Activity of Human Cytochrome P-4502E1 in a Transduced HepG2 Cell Line by Protein Stabilization

Ming-Xue Yang, Arthur I. Cederbaum

Journal:

Alcoholism: Clinical and Experimental Research

Year:

1997

Language:

english

File:

PDF, 893 KB

english, 1997

28

Cytotoxicity and Apoptosis Produced by Arachidonic Acid in HepG2 Cells Overexpressing Human Cytochrome P-4502E1

Qi Chen, Monica Galleano, Arthur I. Cederbaum

Journal:

Alcoholism: Clinical and Experimental Research

Year:

1998

Language:

english

File:

PDF, 310 KB

english, 1998

29

Introduction to the Symposium

Arthur I. Cederbaum

Journal:

Alcoholism: Clinical and Experimental Research

Year:

1998

Language:

english

File:

PDF, 107 KB

english, 1998

30

Ethanol-Induced Apoptosis to Stable HepG2 Cell Lines Expressing Human Cytochrome P-4502E1

Defeng Wu, Arthur I. Cederbaum

Journal:

Alcoholism: Clinical and Experimental Research

Year:

1999

Language:

english

File:

PDF, 1.14 MB

english, 1999

31

Removal of Glutathione Produces Apoptosis and Necrosis in HepG2 Cells Overexpressing CYP2E1

Defeng Wu, Arthur I. Cederbaum

Journal:

Alcoholism: Clinical and Experimental Research

Year:

2001

Language:

english

File:

PDF, 2.02 MB

english, 2001

32

Alcoholic Liver Disease and Apoptosis

Carol A. Casey, Amin Nanji, Arthur I. Cederbaum, M. Adachi, T. Takahashi

Journal:

Alcoholism: Clinical and Experimental Research

Year:

2001

Language:

english

File:

PDF, 52 KB

english, 2001

33

Role of Apoptosis in Alcoholic Liver Injury

Hiromasa Ishii, Masayuki Adachi, Jose C. Fernández-Checa, Arthur I. Cederbaum, Ion V. Deaciuc, Amin A. Nanji

Journal:

Alcoholism: Clinical and Experimental Research

Year:

2003

Language:

english

File:

PDF, 88 KB

english, 2003

34

Role of the Proteasome in Ethanol-Induced Liver Pathology

Terrence M. Donohue Jr, Arthur I. Cederbaum, Samuel W. French, Shirish Barve, Bin Gao, Natalia A. Osna

Journal:

Alcoholism: Clinical and Experimental Research

Year:

2007

Language:

english

File:

PDF, 937 KB

english, 2007

35

Use of CYP2E1-Transfected Human Liver Cell Lines in Elucidating the Actions of Ethanol

Raj Lakshman, Arthur I. Cederbaum, Jan B. Hoek, Masahiro Konishi, Dennis Koop, Terrence M. Donohu

Journal:

Alcoholism: Clinical and Experimental Research

Year:

2005

Language:

english

File:

PDF, 106 KB

english, 2005

36

Effect of pyridine on the expression of cytochrome P450 isozymes in primary rat hepatocyte culture

Defeng Wu, Sorush A. Ramin, Arthur I. Cederbaum

Journal:

Molecular and Cellular Biochemistry

Year:

1997

Language:

english

File:

PDF, 110 KB

english, 1997

37

Ethanol and arachidonic acid produce toxicity in hepatocytes from pyrazole-treated rats with high levels of CYP2E1

Defeng Wu, Arthur Cederbaum

Journal:

Molecular and Cellular Biochemistry

Year:

2000

Language:

english

File:

PDF, 284 KB

english, 2000

38

Adenovirus mediated overexpression of CYP2E1 increases sensitivity of HepG2 cells to acetaminophen induced cytotoxicity

Jingxiang Bai, Arthur I. Cederbaum

Journal:

Molecular and Cellular Biochemistry

Year:

2004

Language:

english

File:

PDF, 498 KB

english, 2004

39

Induction of catalase, alpha, and microsomal glutathione S-transferase in CYP2E1 overexpressing HepG2 cells and protection against short-term oxidative stress

Montserrat Marı́, Arthur I. Cederbaum

Journal:

Year:

2001

Language:

english

File:

PDF, 431 KB

english, 2001

40

Stimulation and proliferation of primary rat hepatic stellate cells by cytochrome P450 2E1–derived reactive oxygen species

Natalia Nieto, Scott L. Friedman, Arthur I. Cederbaum

Journal:

Year:

2002

Language:

english

File:

PDF, 3.42 MB

english, 2002

41

Cyclosporine a protects against arachidonic acid toxicity in rat hepatocytes: Role of CYP2E1 and mitochondria

Defeng Wu, Arthur I. Cederbaum

Journal:

Year:

2002

Language:

english

File:

PDF, 385 KB

english, 2002

42

Cytochrome P450 2E1 responsiveness in the promoter of glutamate-cysteine ligase catalytic subunit

Natalia Nieto, Montserrat Marı&amp, #x0301, , Arthur I. Cederbaum

Journal:

Year:

2003

Language:

english

File:

PDF, 435 KB

english, 2003

43

Proteasome inhibition potentiates CYP2E1-mediated toxicity in HepG2 cells

Marı&amp, #x0301, a José Pérez, Arthur I. Cederbaum

Journal:

Year:

2003

Language:

english

File:

PDF, 327 KB

english, 2003

44

Alcohol-induced liver injury in mice lacking Cu, Zn-superoxide dismutase

Irina G. Kessova, Ye-Shih Ho, Swan Thung, Arthur I. Cederbaum

Journal:

Year:

2003

Language:

english

File:

PDF, 380 KB

english, 2003

45

Adenovirus-mediated expression of Cu/Zn- or Mn-superoxide dismutase protects against CYP2E1-dependent toxicity

María José Pérez, Arthur I. Cederbaum

Journal:

Year:

2003

Language:

english

File:

PDF, 611 KB

english, 2003

46

Interaction of Nitric Oxide with 2-Thio-5-nitrobenzoic Acid: Implications for the Determination of Free Sulfhydryl Groups by Ellman's Reagent

Dalibor Gergel’, Arthur I. Cederbaum

Journal:

Archives of Biochemistry and Biophysics

Year:

1997

Language:

english

File:

PDF, 163 KB

english, 1997

47

Ethanol-related cytotoxicity catalyzed by CYP2E1-dependent generation of reactive oxygen intermediates in transduced HepG2 cells

Arthur I. Cederbaum

Journal:

Year:

1998

Language:

english

File:

PDF, 31 KB

english, 1998

48

Evidence for two ethanol oxidizing pathways in reconstituted mixed-function oxidase systems

Gary W. Winston, Arthur I. Cederbaum

Journal:

Pharmacology Biochemistry and Behavior

Year:

1983

Language:

english

File:

PDF, 504 KB

english, 1983

49

Introduction: Role of lipid peroxidation and oxidative stress in alcohol toxicity

Arthur I. Cederbaum

Journal:

Free Radical Biology and Medicine

Year:

1989

Language:

english

File:

PDF, 230 KB

english, 1989

50

Oxygen-concentration dependence of microsomal chemiluminescence

Susana Puntarulo, Julio F. Turrens, Arthur I. Cederbaum

Journal:

Free Radical Biology and Medicine

Year:

1989

Language:

english

File:

PDF, 456 KB

english, 1989